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Experts' Tips on Taking, Supplements as Sleep-Aids.<br/>'Time' recently spoke with experts regarding <br/>over-the-counter sleep aids and whether they <br/>can really help someone with insomnia.<br/>'Time' recently spoke with experts regarding <br/>over-the-counter sleep aids and whether they <br/>can really help someone with insomnia.<br/>Melatonin has become a popular <br/>supplement in recent years for being <br/>a safe and effective sleep aid.<br/>According to a 2023 study by the American Academy of Sleep <br/>Medicine (AASM), nearly two-thirds of people in the <br/>United States have tried using melatonin to help them sleep. .<br/>It’s not something that is generally <br/>harmful or toxic, which is probably<br/>why people are tempted to take <br/>more when a little bit doesn’t work, Dr. Milena Pavlova, neurologist at Brigham and Women’s <br/>Faulkner Hospital and an associate professor of <br/>neurology at Harvard Medical School, via 'Time'.<br/>'Time' points out that supplements, such as <br/>melatonin, are not regulated by the <br/>U.S. Food and Drug Administration.<br/>Similar to melatonin, over-the-counter antihistamines <br/>like Benadryl have become a popular sleep-aid due to <br/>containing doxylamine, which causes drowsiness.<br/>However, doxylamine also comes <br/>with a number of side effects, <br/>including a potential hangover the next day.<br/>The big problem with antihistamines <br/>is they can make people extremely <br/>groggy and really impair cognitive <br/>function the next day, Dr. Indira Gurubhagavatula, professor of medicine <br/>in the division of sleep medicine at the <br/>University of Pennsylvania, via 'Time'.<br/>While antihistamines can induce <br/>drowsiness, they don't normally <br/>result in quality, restorative sleep.<br/>Experts suggest eliminating things that prevent healthy sleep, like alcohol and caffeine, while also incorporating physical activity into your daily routine.
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Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'
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